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August 11, 2026

Tanai Therapeutics appoints Josua Jordi as Chief Executive Officer

V-Bio Ventures portfolio company Tanai Therapeutics announces that Josua Jordi Ph.D. was appointed Chief Executive Officer and Director to lead Tanai’s

next phase of development.

Ghent, Belgium, August 11th, 2026 – Tanai Therapeutics (“Tanai” or the “Company”), a  biotechnology company developing small molecule therapies for obesity and cardiometabolic  disease, today announced the appointment of Josua Jordi, Ph.D., as Chief Executive Officer  and Director on July 1st, 2026. Dr. Jordi succeeds Pieter Rottiers, Ph.D., who served as  Tanai’s founding CEO and led the Company through its initial build-out and transition  towards a standalone biotech company. Dr. Jordi has served as Chief Scientific Officer of  Tanai, where he led the Company’s scientific strategy and drug discovery activities through  key inflection points.

“I am proud to have served as a founding CEO for Tanai and to have helped bring the  Company to this important stage,” said Pieter Rottiers, Ph.D. “Over the past period, Tanai  has strengthened its scientific direction, advanced its target validation work and identified  differentiated chemical matter. This progress reflects the dedication of the Tanai team, as  well as the support of our investors and partners. I have full confidence in Josua’s leadership  as the Company moves into its next phase.”

“On behalf of Tanai’s Board of Directors, I want to thank Pieter for his dedication and  leadership, and for building the strong foundation on which Tanai now stands,” said Sara  Vandenwijngaert, Chair of Tanai’s Board of Directors; “We are equally excited that Josua will  step into the role of CEO. Josua combines exceptional scientific expertise and a proven  track record in obesity drug discovery & development with a demonstrated ability to build a  successful company in this space. We look forward to Tanai entering an exciting new phase  under his leadership.”

“I am honored to take on the role of CEO at this important moment for Tanai”, said Josua  Jordi, Ph.D. “Building on the foundation established by the Tanai team, I believe we are  well-positioned to advance its differentiated small molecule approach for obesity and  cardiometabolic diseases. I look forward to continuing to work closely with the team, our  investors, scientific founders and partners as we continue to develop Tanai’s therapeutic  strategy and portfolio.  ”

Dr. Jordi is an ETH Zurich-trained biochemist and received a distinguished Ph.D. in human  physiology from the University of Zurich. He co-founded EraCal Therapeutics Ltd, based on  platform technology invented during his postdoctoral fellowship at Harvard University, and  led the obesity-focused biotech as CEO and board member from inception through financing  rounds, multiple research collaborations, and a licensing deal with Novo Nordisk. He later  led drug discovery efforts in metabolism at pRED-Roche before joining Tanai as Chief Scientific Officer. He now serves as Chief Executive Officer and Director.

About Tanai Therapeutics

Tanai Therapeutics is developing a differentiated small molecule approach for obesity and cardiometabolic disease by targeting energy expenditure pathways. The Company’s strategy is guided by human genetics and translational biology, with the aim of developing therapies that may complement existing appetite-modulating treatments or provide alternative approaches for patients with obesity and related metabolic diseases. Based in Belgium, Tanai brings together world-class metabolic disease experts, drug discovery scientists and biotech entrepreneurs to advance next-generation therapeutics for cardiometabolic health.

For more information, please contact:

Tanai Therapeutics, info@tanaitx.com

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Pieter van Reysschootlaan 2/104
9051 Sint-Denijs-Westrem (Gent)
Belgium

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